Pain Rehabilitation and Oxidative Stress (Oxi-S): A Multimodal Approach in Physical and Rehabilitation Medicine

Date: Sunday 2 Nov. 2025

Id 19
Topic Pain
Main Speaker Roberto Casale Italy
Co Speakers Kestutis Petrikonis Lithuania
Attendees 30
Extra Fees 50 euros


Physical and rehabilitation medicine must be considered in a context of a multimodal approach in which the physiatrist must be able to govern the multimodal approach to the patient as a whole.

Two of the aspects of basic sciences that must become part of the cultural background of those who deal with rehabilitation are the influence of cellular oxidative stress in generating and maintaining chronicity and the understanding of the mechanisms generating a chronic pain status. This is in order to optimize treatment both through the typical disciplines of rehabilitation but also through the wise use of conventional and complementary pharmacology. Oxi-S in various forms is present in all degenerative and chronic pathologies: cardio-pneumological, degenerative osteoarticular as well as in pain.

Oxi-S is one of the mechanisms with which pain becomes chronic in a state of central sensitization. The presence of Oxi-S and the ability of rehabilitation to reduce its levels and therefore to positively interfere with the rehabilitation outcome must be used. This ability has been widely demonstrated in cardiopulmonary diseases as well as in the treatment of the so-called Long-COVID. The positive role of a multimodal rehabilitation approach that includes movement has also been demonstrated at a clinical level in pain control.


Chair Jurga Bernatoniene

16H30 Introduction. Defining the frame. Kestutis Petrikonis

16H45 “Rehabilitation Approaches tonReduce Oxi-S” Roberto Casale

17H “Dual Action of Rehabilitation on Pain and Underlying Pathology” Kestutis Petrikonis Roberto Casale

17H15 “Pain, Oxi-S, and Aging of Biological Systems” Elephteria Antoniadou

17H30 “Multimodal and Ecological Integrated Rehabilitation Therapy. A reappraisal” Kestutis Petrikonis Roberto Casale Elephteria Antoniadou

18H “Open discussion and conclusion. To facilitate questions & answers, remarks and made take-home messages clearer, the session is based on: Clinical Cases Role playing” Kestutis Petrikonis Roberto Casale Elephteria Antoniadou

Event Timeslots (1)

  • Arganier

    -

    Short Workshop



    Id 19
    Topic
    Pain

    Main Speaker
    Roberto Casale Italy

    Co Speakers
    Kestutis Petrikonis Lithuania

    Attendees 30
    Extra Fees 50 euros

    Chair
    Jurga Bernatoniene

    16H30
    Introduction. Defining the frame.
    Kestutis Petrikonis
    16H45
    "Rehabilitation Approaches tonReduce Oxi-S"
    Roberto Casale

    17H
    "Dual Action of Rehabilitation on Pain and Underlying Pathology"
    Kestutis Petrikonis Roberto Casale

    17H15
    "Pain, Oxi-S, and Aging of Biological Systems"
    Elephteria Antoniadou

    17H30
    "Multimodal and Ecological Integrated Rehabilitation Therapy. A reappraisal"
    Kestutis Petrikonis Roberto Casale Elephteria Antoniadou

    18H
    "Open discussion and conclusion. To facilitate questions & answers, remarks and made take-home messages clearer, the session is based on: Clinical Cases Role playing" Kestutis Petrikonis Roberto Casale Elephteria Antoniadou

    ISPRM25 ISPRM25